Manchester United:
Jose Mourinho's side were beaten 2-1 by leaders Manchester City on Sunday, a result that left them 11 points behind their cross-city rivals.
"When you lose, you probably have a little bit more desire to win," the United manager said ahead of Bournemouth's visit.
"Nobody likes to lose once, nobody wants to lose twice. I think that's something that belongs to every team in the world. When you lose a match the next one, you have that little bit extra to give."
Paul Pogba will again be out through suspension, while Marcos Rojo is a doubt.
Bournemouth:
Cherries boss Eddie Howe is hoping for a positive result against second-placed United.
"In the previous two seasons we have got some good results in these games and they have helped to define our seasons, so we are looking for the same again," he said.
"It can really lift confidence levels to a point where it has a really positive effect on the rest of your season, there will be no surrender from us."
Adam Smith is available again following suspension and Harry Arter could be drafted back into the starting XI after being left on the bench for the 2-2 draw at Crystal Palace on Saturday.
Recent form:
Possible lineups:
Manchester United: De Gea; Lindelof, Smalling, Rojo; Valencia, Matic, Herrera, Young; Mata, Martial, Ibrahimovic.
Bournemouth: Begovic, Smith, Cook, Ake, Daniels, Stanislas, Cook, Surman, Fraser, King, Defoe.