Real Madrid - Barcelona
There is not much more to say. The Clasico is the biggest game in world football and all over the world people would stop to watch these two giants go head to head once more.
Barcelona - Juventus
The Italians saw off Barcelona last year after the Catalans has stunningly knocked out PSG in the previous round. Barca will no doubt be out for revenge this time round.
Real Madrid - Manchester City
Pep Guardiola will be running scared of the Bernabeu. With Bayern he was unceremoniously dumped out of the tournament and he will be looking to make sure history does not repeat itself.
Barcelona - Manchester City
Pep's return to Camp Nou would be the draw of the round. In 2015 he returned with Bayern but this time round he could really define his career with a win against his former club.
Roma - Sevilla
Roma's technical director is Monchi, a former Roma goalkeeper and boyhood Sevilla fan, so there would no doubt be some divided loyalties if this tie came up.
Sevilla - Real Madrid
Another tie with plenty of history or animosity, read it how you will. The famous 8-0 from 1950 or even just Sergio Ramos both unite and divide these two teams
Sevilla - Barca
We could get a preview of the Copa del Rey final on the European stage and the one draw that almost no-one wants in Catalonia or Andalusia. Both teams will know they stand a better chance if their opponent doesn't come from La Liga.
Bayern - Manchester City
Another tie pitting Pep against one of his old clubs. Since he left Barcelona, these two clubs have been his major projects and he has no doubt left his mark on both.
Real Madrid - Bayern
James and the biggest refereeing debate of the year will be the talk of the press if these two teams meet again. The Colombian will be looking to prove himself against Zinedine Zidane, who dropped him and loaned him out. It would also see Robben and Kroos go up against their former teams.