According to the 'BBC', around 2,000 fans are expected to travel to watch their sides in action with Liverpool playing Spartak Moscow on Tuesday before United face CSKA 24 hours later.
The two clubs have warned fans making the 3,200-mile round trip that a visible police presence is to be expected "wherever groups of Liverpool and Manchester United fans congregate, including at your accommodation".
Manchester United have warned fans to take measure to ensure their personal safety, including not wearing club colours and avoiding walking the streets of Moscow alone.
The world will be watching on in the hope that the same Russian hooligans that marred Euro 2016 do not rear their ugly heads ahead of next summer's World Cup in Russia.